A 50 year old woman with a history of ovarian cancer presents with 3 days of worsening shortness of breath and a dry cough. You are called urgently to the emergency department for intubation and admission to the ICU. On arrival she is working hard to breath with a respiratory rate of 40, saturating 87% on a 100% non-rebreather. Her heart rate is 130 with a blood pressure of 170/90.
What is your approach to undifferentiated hypoxemia?
Who would you consider non-invasive ventilation for?
How would you approach an intubation in a severely hypoxic patient?